Ovarian Reserve Markers

ovarian reserve

Ovarian reserve is a term that is used to determine the capacity of the ovary to provide eggs that are capable of fertilization resulting in a successful pregnancy. Several noninvasive ovarian reserve markers have been proposed to assess ovarian reserve including serum levels of follicle stimulating hormone (FSH), serum anti-mullerian hormone (AMH), luteinizing hormone, estradiol, […]

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Luteal Phase Deficiency

Luteal Phase Deficiency | Missing Piece| Unexplained Infertility

Countless hours, blogs and forums have been dedicated to infertility and the potential source as a luteal phase deficiency.  Luteal phase deficiency (LPD), or a lack of progesterone has been described in menstruating women.  It’s association has been with other medical conditions (rapid weight loss, post partum, renal transplantation, and even in random, normal cycles).  […]

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“Decreased Ovarian Reserve”: Is there a “best test”?

IVF egg retrieval and best test for ovarian reserve

The American Society of Reproductive Medicine (ASRM), the professional committee for experts in reproductive endocrinology and infertility medicine, put out a committee opinion this month on testing and interpreting measures of ovarian reserve. A woman’s eggs, or oocytes, are the greatest when she is a fetus and decline in number as she ages. Ovarian reserve […]

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Anti-Mullerian Hormone as a Marker of Ovarian Reserve

Anti-mullerian hormone (AMH), also known as mullerian inhibiting substance, is a regulatory protein found in the ovary.  It is synthesized in the granulosa cells of antral follicles (see drawing below).  AMH is thought to play a role in coordinating follicular development within the ovary; there is a “give and take” between follicle stimulating hormone (FSH) […]

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Your IVF Protocol

If you and your physician have decided that you need IVF, you will be given a protocol of your upcoming IVF cycle. A protocol is a schedule or blueprint of how your cycle will be done. It includes the medications you will be taking, the instructions on how to take these medications, and the procedures […]

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The Reproductive Life Cycle

There are five reproductive stages in a woman’s reproductive life cycle.  These include premenarche (before the first menstrual period) stage; the reproductive, premenopausal stage; the early menopausal transition stage; the late menopausal transition stage; and finally, menopause.  There is no single test to determine reproductive potential, but the menstrual cycle pattern and hormone levels can […]

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The Clomiphene Citrate Challenge Test (CCCT)

Many patients 40 years of age and older will be asked to perform a clomiphene citrate challenge test (CCCT) as part of their evaluation. The original design of the test was to predict ovarian reserve and prognosis for future pregnancy. Most insurance companies now require an annual “passing” score on the CCCT to permit coverage […]

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Converting Follicle Stimulating Hormone (FSH)/Intrauterine Insemination (IUI) Cycles to In Vitro Fertilization (IVF)

For many couples, the inability to conceive is caused by abnormal or absent ovulation. Normal ovulation involves the natural recruitment of an egg that has been hibernating in the ovary since before birth. Ovulatory dysfunction is often corrected with hormonal medication which stimulates the ovary to ovulate. The hormone used is follicle stimulating hormone (FSH) […]

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Ovarian Reserve

“Ovarian Reserve” is a term referred by many infertility specialists to describe the size, quality and developmental potential of the eggs remaining in the ovary. As a woman age’s ovarian reserve diminishes and the chance of a chromosomal abnormal egg and thus the potential for miscarriage increases. As a result, older women are less likely […]

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