Fertility Cares Blog

The fundamental importance of progesterone to pregnancy has been known since the pioneering work published in 1946 by the late Dr. Georgiana Segar Jones in the Journal of the American…

Miscarriage is a very common occurrence.  At least 15-25% of pregnancies will end in miscarriage, and as a woman ages, this percentage increases.  Many women are not aware of this…

Uterine fibroids are associated with miscarriages and may be a cause of recurrent pregnancy loss.  A recent study from the United Kingdom (Human Reproduction 26:3274;2011) found that the intrauterine cavity was distorted…

Therapeutic options to treat genetically inherited thrombophilias such as Factor V Leiden or other genetic mutations that increase blood clotting include antithombotic medications such as low dose aspirin and low…

The physical examination should include height weight, calculation of body mass index (BMI), blood pressure, and a general assessment for signs of metabolic illness. Body build (habitus) should be defined,…

Thrombophilia is a disorder involving the genetic predisposition to form a blood clot (deep venous or arterial thrombosis) potentially leading to stroke, heart attack or pulmonary embolus. Thrombophilia may also…

The immune system evolved to protect the individual from non-self, genetically different, or allogenic tissue. Immunity can be either innate (in born) or adaptive (acquired) depending on the molecule causing…

Testing for recurrent pregnancy loss includes assessment of possible genetic, anatomic, hormonal, inflammatory, and immunologic causes. All testing can be accomplished within one menstrual cycle with tests timed during the…

Potential anatomical causes of recurrent pregnancy loss can be divided into either congenital (born with) or acquired anomalies. These potential causes are associated with adverse pregnancy outcome and are thus…