Can Inflammation Cause Lack of Ovulation?
Can inflammation cause lack of ovulation? Inflammation is bad. The effects of inflammation are worse and compounding. The associations have been correlated to cardiovascular disease. But also we must consider other organs and systems, perhaps even more delicate. Insulin resistance and inflammation are now correlates. We know that impaired glucose tolerance not only boosts a […]
What Is A Normal Menstrual Cycle?
The purpose of the menstrual cycle is to prepare the uterus for pregnancy. Many patients ask what is a normal menstrual cycle? It depends on an orderly progression of hormonal signals and is simplistically divided into the following phases: 1) Proliferative/ Follicular Phase 2) Ovulatory Phase 3) Secretory/Luteal Phase 4) Menstrual Phase Cycle Day #1 […]
Progesterone and its Role in Pregnancy
Progesterone is a hormone produced by the ovaries and later, if pregnancy occurs, by the placenta. Progesterone is essential to achieve and maintain a healthy pregnancy. In the second half of the menstrual cycle after ovulation, progesterone prepares the uterine lining (endometrium) to receive the fertilized egg (embryo). If implantation is successful and pregnancy occurs, […]
Recurrent Implantation Failure: Why Me?
Implantation of the embryos depends upon on a well-developing embryo and a synchronous healthy endometrium. It seems deceptively simple. However, for such success to manifest, a highly-organized and amazingly intricate web of molecular interactions must first occur. When pregnancy does not occur, our inclination is to look for both an answer and for a correction. […]
I’ve waited so long to become pregnant and have been through so much. Now that I finally am, I’m as sick as a dog. Why is this happening to me? Don’t worry. Your body is not trying to reject the pregnancy that you have worked so hard to have. Nausea and vomiting is extremely common […]
Uterine fibroids are associated with miscarriages and may be a cause of recurrent pregnancy loss. A recent study from the United Kingdom (Human Reproduction 26:3274;2011) found that the intrauterine cavity was distorted by fibroids in 8.2% of women with a history of recurrent pregnancy loss. They also found that surgical removal of these intrauterine fibroids increased the […]
Much of our efforts in assisted reproductive technologies, namely IVF and IUI, is focused on cultivation of mature oocytes and generation of quality embryos. However, without a rich environment, these embryos cannot exist. This soil is the endometrium, the lining of the uterus that is prepared monthly and then quickly shed like an afterthought, if […]
The intention of any screening test is to provide fast, cost-effective and reliable tests that require little intervention. In the billion-dollar industry of home fertility assessment the hat can be hung on ovulation predictor kits (LH kits). Leutenizing hormone is the unsung hero of the menstrual cycle. It is released in the pituitary gland in […]
Defining that short window that the ovulated egg is available to receive the sperm (12-24 hours) is imperative. However, the physical discomfort (Mittleschermz) that is associated with ovulation is experienced by surprisingly few women. Moreover, less than one-third of regularly cycling, highly-motivated women accurately can predict ovulation without formal monitoring. Basal body temperature monitoring is […]
The cyclic menstrual cycle is predictable. In the first half of the cycle, care is taken to groom the best egg for fertilization. Once this egg reaches the maturity parameter; ovulation is triggered and the released oocyte sets out on its journey into the fallopian tube. Here it is fertilized by the sperm and then […]