Understanding how your period affects your chances of pregnancy is an important of understanding your fertility. Menstruation, or the period, is the result of an endless dialogue between the command centers within the brain (the hypothalamus and pituitary gland); the ovary and the uterus. In particular the uterine lining, the endometrium, is responsive to the […]
Equal amounts of research and consternation center on the proper cultivation, collection and treatment of oocytes during the IVF cycle. Only mature oocytes are a candidate for fertilization. Moreover, only a minor percentage of fertilized eggs will be candidate embryos for transfer. And now of these candidate embryos, a fraction of them harbor normal genetics […]
Maximizing Chances of Pregnancy
Much emphasis in the field of reproductive technologies and IVF is placed on arriving at delivery of a healthy infant. Our goal is to promote generation of the healthiest, euploid (chromosomally-normal) embryo and transferring it to a primed, and accepting uterine cavity. Here it is anticipated to implant, develop and flourish until baby’s safe delivery. […]
Progesterone and its Role in Pregnancy
Progesterone is a hormone produced by the ovaries and later, if pregnancy occurs, by the placenta. Progesterone is essential to achieve and maintain a healthy pregnancy. In the second half of the menstrual cycle after ovulation, progesterone prepares the uterine lining (endometrium) to receive the fertilized egg (embryo). If implantation is successful and pregnancy occurs, […]
Exercising the “Art” in A.R.T.
There is a certain “art” in Assisted Reproductive Technologies. Part of which is the successful culturing of embryos. Providing the best environment for embryos to thrive is one part of the infertility puzzle that can be very complex. Based on many years of research, embryologists study the biology of embryos to determine their specific needs […]
Recurrent Implantation Failure: Why Me?
Implantation of the embryos depends upon on a well-developing embryo and a synchronous healthy endometrium. It seems deceptively simple. However, for such success to manifest, a highly-organized and amazingly intricate web of molecular interactions must first occur. When pregnancy does not occur, our inclination is to look for both an answer and for a correction. […]
Cryopreservation: What is it?
Cryopreservation (freezing) of embryos has been associated with IVF since its inception in the 1908’s. The use of Frozen Embryo Transfer (FET) has resulted greater than 150,000 health births worldwide. The availability of freezing viable human embryos is a necessary and desirable process. Cryopreservation indirectly allows for the control of how many embryos can be […]
Natural and Minimal IVF: Caveat Emptor
Environment friendly business promotions have a receptive audience. Cost consciousness together with ‘green’ polices embracing such terms as ‘small is beautiful’ and ‘less is better’ can be a good thing. However, when these neologisms are applied to In Vitro Fertilization (IVF) using terms like, “Natural Cycle IVF” or “Minimal Stimulation IVF” under the guise of […]
Spinal muscular atrophy (SMA) is an inherited disease that affects an infant’s muscular activity. Voluntary muscles are driven by motor neurons. Children with SMA are missing a gene that is required to produce certain proteins involved in motor neuron development. Without this protein, the nerves shrink and ultimately atrophy. Without motor neuron innervation, the muscles […]
Historically, we have been limited the means of assay endometrial receptivity. It is a dynamic organ that needs to be evaluated. Embryo implantation occurs when the endometrial receptivity is precisely well orchestrated. When the window of receptivity does not meet optimal implantation timing of the embryo, pregnancy will not occur. Endometrial biopsies where a random […]