Common Vaginal Yeast Infection Treatment is Linked to Miscarriage

Vaginal yeast infections, also known as vulvovaginal candidiasis, are a common condition that affects many women, especially those who are pregnant. However, treating a yeast infection during pregnancy requires caution, as certain medications can pose risks to both the mother and the baby.

Risks of Fluconazole as a Yeast Infection Treatment Pill

Fluconazole (brand name Diflucan) is a commonly prescribed yeast infection treatment pill, typically given in 150 mg doses. While effective in treating candidiasis, its use during pregnancy has been linked to serious risks:

• Miscarriage: Even low doses of fluconazole (<150 mg) may increase the likelihood of miscarriage. Doses of 150 mg or more are associated with a two- to threefold increase in risk. This raises concerns for expectant mothers who may wonder: Can a yeast infection cause miscarriage? While the infection itself is unlikely to lead to pregnancy loss, the medications used for treatment, such as fluconazole, can increase the risk.
• Birth Defects: Taking fluconazole during the first trimester has been linked to an 80% higher risk of neonatal cardiac closure defects (commonly referred to as a hole in the heart).

Given these findings, the journal Contemporary OB/GYN issued a clinical alert to physicians, advising against fluconazole use during pregnancy.

Safer Yeast Infection Treatment Options During Pregnancy

Fluconazole is considered safe for non-pregnant individuals but should not be used while pregnant. Fortunately, there are safer alternatives for managing yeast infections during pregnancy:

• Clotrimazole (Mycelx, Lotrimin)
• Miconazole (Monistat)

These topical antifungal treatments are recommended for a seven-day course, which is considered the most effective and safest approach during pregnancy.

While yeast infections during pregnancy can be uncomfortable, it’s crucial to choose treatments that prioritize the health of both mother and baby. Avoid using fluconazole and opt for safer topical treatments like clotrimazole or miconazole. Always consult your healthcare provider before starting any treatment.

At Fertility Centers of New England, we recommend that patients consult with their doctor before taking any medication during pregnancy. If you have medication questions or further questions about pregnancy, please contact us today!