About Fertility


How Common Are Chromosome Abnormalities in IVF?

A team of researchers recently reported at the American Society of Human Genetics found that a common gene variant may be linked to both early pregnancy loss and failed In Vitro Fertilization (IVF) treatments. In a study analyzing over 46,000 embryos from 2,400 women having IVF, the gene variant known as rs2305957 was associated with the risk of aneuploidy. Aneuploidy is an abnormal number of chromosomes and is a major cause of pregnancy loss and failed pregnancies following IVF treatments. The clinical usefulness of this study is yet to be fully determined but may ultimately help define women prone to pregnancy failure due to aneuploidy. This study also provides yet another reason why aneuploidy testing of biopsied embryos is important in women having IVF.

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