Progesterone Therapy In Women with Recurrent Pregnancy Loss

Progesterone Therapy In Recurrent Pregnancy Loss

  The fundamental importance of progesterone to pregnancy has been known since the pioneering work published in 1946 by the late Dr. Georgiana Segar Jones in the Journal of the American Medical Association. Progesterone has many interesting and important effects that are critical to pregnancy not only hormonal in nature but also potentially immunosuppressive. Progesterone […]

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Luteal Phase Deficiency

Luteal Phase Deficiency | Missing Piece| Unexplained Infertility

Countless hours, blogs and forums have been dedicated to infertility and the potential source as a luteal phase deficiency.  Luteal phase deficiency (LPD), or a lack of progesterone has been described in menstruating women.  It’s association has been with other medical conditions (rapid weight loss, post partum, renal transplantation, and even in random, normal cycles).  […]

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Progesterone and its Role in Pregnancy

Progesterone is a hormone produced by the ovaries and later, if pregnancy occurs, by the placenta. Progesterone is essential to achieve and maintain a healthy pregnancy. In the second half of the menstrual cycle after ovulation, progesterone prepares the uterine lining (endometrium) to receive the fertilized egg (embryo). If implantation is successful and pregnancy occurs, […]

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Pregnant or Not Pregnant?

Endometrial Scratching

Fertility treatments allow patients to be empowered and to regain hope.  Once the patient has engaged in treatment, the two-week wait prior to pregnancy confirmation can be unbearable. Pregnant or not pregnant? Not surprisingly, patients search for both emotional and physical signs to affirm or deny the potential of pregnancy; all while watching the calendar turn […]

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Improving Fertility Through Nutritional Medicine

When a women’s body is preparing for pregnancy there is an increased need for certain vitamins and minerals so the ovary will ovulate a mature egg that can be fertilized.  The “healthier” the egg the better the chance of making a healthy baby. The nutrients in your blood enrich the granulosa cells that surround and […]

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What About the Soil? Then Endometrium: An Unsung Hero

Much of our efforts in assisted reproductive technologies, namely IVF and IUI, is focused on cultivation of mature oocytes and generation of quality embryos.  However, without a rich environment, these embryos cannot exist. This soil is the endometrium, the lining of the uterus that is prepared monthly and then quickly shed like an afterthought, if […]

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Progesterone Support in IVF

Progesterone is critical for the establishment and continuation of a successful pregnancy. Exogenous progesterone has been given in IVF since IVF’s inception. The reason was thought to be due to the removal of cells from the ovary that produced progesterone at the time of egg retrieval. Later when IVF cycle stimulation included drugs such as […]

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Decoding the Menstrual Cycle

Menstruation, or the period, is the result of an endless dialogue between the command centers within the brain (the hypothalamus and pituitary gland); the ovary and the uterus. In particular the uterine lining, the endometrium, is responsive to the growth and maturation hormones provided by the ovary. The two major hormones responsible for preparing the […]

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