Our success in fertility treatment is secondary to the ability to generate embryos. The generation of embryos is a result of our ability to stimulate the ovaries to produce more than one oocyte (which is what is achieved each menstrual cycle). The dominant follicle is the most responsive of the 200 or so candidate oocytes […]
Can Cancer Genes Be Turned On Or Off?
Can cancer genes be turned on or off? In an interview for AARP Magazine by ‘Pop’ singer, Melissa Etheridge implied that genes for cancer (BRCA1 and BRCA2) can be turned on or off by diet. Her fallacious statements have caused an outcry by physicians, genetic counselors, cancer survivors and support groups for women with the […]
Hereditary Gynecologic Cancers
There are approximately one million people in the Untied States carrying genes for the most common hereditary gynecologic cancers: BRCA and Lynch syndrome. Early diagnosis of their carrier status and interventions such as increased surveillance and prophylactic surgeries can dramatically reduce their risk of dying from cancers caused by their genetic mutations. A focus on […]
Aggressive stimulation of the ovary concerns some for the inadvertent creation of ovarian cancer. To address this concern, the OMEGA study was established. This study is a large cohort study that evaluated the effects of fertility drug usage and its potential relation to ovarian cancer risk. Approximately 20,000 women were studied with a follow up time of […]
Fertility Drugs and Ovarian Cancer
Over the years, controversy has existed whether fertility drugs can predispose to ovarian cancer. Several small poorly designed studies published in the 1990s raised the concern that drugs used to stimulate the ovaries and induce ovulation increased the risk of later developing ovarian cancer. Most recent studies have tended to suggest otherwise and the largest […]