January 27, 2011

Donor Oocyte Part II

Taking the clinical step to donor oocyte is a very big step and one taken only after considerable thought and discussion. Donor oocyte is never a couple’s only option but may be the best option to achieve the goal of having a healthy child. A couple must balance what may be a very low prognosis with a patient’s own egg versus a 10-fold higher pregnancy rate with a donated oocyte (see Figure 45 below). Determining that balance should take into account many factors predicting prognosis, including maternal age, prior history and response to previous treatments. Live birth pregnancy rates can retrospectively be examined from all US IVF centers, looking specifically at outcomes in patients with decreased ovarian reserve – – some of these centers reveal a zero percent annual live birth rate in their decreased ovarian reserve patients using their own oocytes.
figure 45

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Medical Director, Fertility Centers of New England