Antioxidants May Improve Egg Quality In Women With Endometriosis
Endometriosis is associated with infertility in at least 50% of those with this debilitating disease. It is a common condition in women often associated with pain and infertility. It occurs when tissue that normally lines the inside of the uterus (endometrium) grows on the outside of it, mainly in the pelvis, ovaries and abdomen. Egg and embryo quality are poor in women with endometriosis. Vitamin D has been shown to improve embryo quality in these women and researchers from the University of Southampton and Princess Ann Hospitals Complete Fertility Centre in the UK have recently published in the journal, “Scientific Reports” that antioxidants may improve egg quality in women with endometriosis.
Despite ovulation induction many women with endometriosis have difficulty making mature oocytes suitable for fertilization. Follicular fluid from women with endometriosis have been found to have high amounts of free-radical chemicals called Reactive Oxygen Species (ROS). These ROS chemicals can cause the eggs not to mature properly and thus fail to fertilize and develop. ROS could be blocked by two antioxidants. Resveratrol found in the skins of grapes and berries and Melatonin, a chemical released during sleep. These findings provide new hope for women with endometriosis-associated infertility.
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