Tag Archives: endometrium


Chronic Endometritis

R. Ian Hardy, M.D., Ph.D. Board-Certified Reproductive Endocrinologist, Medical Director

R. Ian Hardy, M.D., Ph.D. Board-Certified Reproductive Endocrinologist, Medical Director

Chronic endometritis is chronic inflammation (“itis”) of the endometrium (the uterine lining).  Chronic inflammation may hinder normal implantation of an embryo and its subsequent development. A patient with good embryo morphologic quality with either a negative pregnancy or with an early miscarriage may be evaluated for chronic endometritis before proceeding with further treatment. Evaluation of chronic [...]

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Posted in Fertility


What Makes a Good Endometrium and How is it Monitored?

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Historically, we have been limited the means of assay endometrial receptivity.  It is a dynamic organ that needs to be evaluated  as such.  Embryo implantation occurs when the endometrial receptivity is precisely well orchestrated.  When the window of receptivity does not meet optimal implantation timing of the embryo, pregnancy will not occur. Endometrial biopsies where [...]

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Posted in Fertility


What About the Soil? Then Endometrium: An Unsung Hero

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Much of our efforts in assisted reproductive technologies, namely IVF and IUI, is focused on cultivation of mature oocytes and generation of quality embryos.  However, without a rich environment, these embryos cannot exist. This soil is the endometrium, the lining of the uterus that is prepared monthly and then quickly shed like an afterthought, if [...]

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Posted in Fertility


DECODING THE MENSTRUAL CYCLE

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Menstruation, or the period, is the result of an endless dialogue between the command centers within the brain (the hypothalamus and pituitary gland); the ovary and the uterus. In particular the uterine lining, the endometrium, is responsive to the growth and maturation hormones provided by the ovary. The two major hormones responsible for preparing the [...]

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Posted in Fertility


Endometriosis and Infertility

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Danielle Vitiello, Ph.D., M.D. Board-Eligible Reproductive Endocrinologist

Endometriosis is a common condition in women often associated with pain and infertility. It occurs when tissue that normally lines the inside of the uterus (endometrium) grows on the outside of it, mainly in the pelvis, ovaries and abdomen. Monthly hormonal changes can produce inflammation leading to pain and infertility due to the tissue itself [...]

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Posted in Fertility

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